Skip to main content

Professor Nick Bishop

Professor Nick Bishop

Role: Professor of Paediatric Bone Disease

The UK’s only Professor of Paediatric Bone Disease.
Qualifications and training

Clinical training at Manchester University
MRC and Welcome Fellowships, Cambridge University
Visiting Professor at McGill University in Montreal
Appointed to Chair in Sheffield in 1998


Research subjects

– Clinical research on treatment of childhood osteoporosis
– Basic science group on pathophysiology of childhood bone diseases


My main aim is to improve understanding of the causes of bone fragility in children and provide better treatment for children with disabling bone diseases.
For the last 17 years, I have focused on bone fragility in childhood, from apparently healthy children with one or more fractures, to children with a defined clinical condition such as osteogenesis imperfecta, in whom fractures occur frequently.
We have led a group of four designated centres in England to create a specialised network to treat children with severe, complex and atypical osteogenesis imperfecta. The Department of Health has committed around £18 million to fund this network over a period of five years.
We have recently started to treat children with the disease hypophosphatasia using a new enzyme-replacement therapy. So far we have treated more infants and young children in Sheffield than anywhere else in the world.
We undertake a lot of research into the causes and treatment of bone disease in children, always seeking to find better ways to improve the quality of life of our patients and their families.
Our research is funded by medical research charities, including Arthritis Research UK, Orthopaedic Research UK, The Children’s Hospital Charity, and the biotechnology and pharmaceutical industries.

Sheffield Children’s NHS Foundation Trust
Sheffield Children's@SheffChildrens
We’re thinking of everyone getting their A level results today! You should all be proud of what you’ve achieved. En…
As of 6 July 2022 everyone (colleagues, patients and families) must wear a mask. This applies to all spaces across. all sitesMore information on how we are keeping you safe is available here.