Our Research and Innovation Department is dedicated to the development of medicines and treatments for children, and innovating in children’s healthcare is a key priority for the Trust.

Our research strengths cover a wide range of clinical specialties and we are proud to work with some of the country’s leading professionals in paediatric conditions.

The Sheffield Children’s Clinical Research Facility (CCRF) opened in 2008 and was the first paediatric clinical research facility in the UK.


Research and Innovation at Sheffield Children’s NHS Foundation Trust includes the Research Administration and Governance Team and the Clinical Research Facility Team. Together we provide comprehensive assistance to researchers conducting clinical research in our Trust.

We work closely with colleagues in the NIHR CRN: Yorkshire and Humber, regional NHS trusts and our local universities to ensure that we provide a streamlined service for the development, set-up, costing and management of both paediatric and adult research conducted at Sheffield Children’s NHS Foundation Trust.

Health Research Authority

The Health Research Authority and the Government set standards for all NHS organisations to make sure we protect your privacy and comply with the law when we are involved in research. They review all research studies to make sure that the research uses of personal data are in the public interest and meet ethical standards.


The South Yorkshire Institute for Innovation and Research in Child Health – Siirch – is an organisation established by Sheffield Children’s NHS Foundation Trust, Sheffield Hallam University and the University of Sheffield.

Siirch brings together researchers, healthcare professionals, local authorities and voluntary organisations to work together in collaboration on child health research to ultimately improve the lives of children in our region.

Siirch was set up by Professor Paul Dimitri, Consultant in Paediatric Endocrinology and Director of Research and Innovation at Sheffield Children’s Hospital. A number of staff members are also involved.

Sheffield Children’s NHS Foundation Trust
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