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Sepsis is a clinical syndrome caused by the body’s immune and coagulation systems being switched on by an infection. Sepsis with shock is a life-threatening condition that is characterised by low blood pressure despite adequate fluid replacement, and organ dysfunction or failure. Sepsis is a significant condition which can cause death in people of all ages.

Embrace supports The UK Sepsis Trust in their ‘Sepsis 6’ initiative. The guidance and clinical toolkits are produced in collaboration with NICE and support the implementation of NICE guideline NG51 (2016).

It is important to recognise the signs and symptoms of sepsis early and respond immediately, including review by an experienced clinician.

Embrace welcomes referral calls for clinical advice and/or critical care transfer relating to neonates and children with sepsis.

Please use the following documents to support your care of children with proven or suspected sepsis in the first hour:

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